Vesiculobullous disorders mnemonic

Which antigen is attacked in the main blistering diseases

The mnemonic

Pemphigus is Desmosome, Pemphigoid is Basement

What each word stands for

  • PemphigusDesmogleins in desmosomes, intraepidermal split
  • PemphigoidBP180 and BP230 at the basement membrane, subepidermal split

Why it matters clinically

Predicts blister fragility, Nikolsky sign and immunofluorescence pattern.

Where it stops being reliable

Omits dermatitis herpetiformis and acquired epidermolysis bullosa.

Teaching aid, still awaiting independent review. Confirm facts in a standard source.

More mnemonics

Common questions

What is the Vesiculobullous disorders mnemonic?

Pemphigus is Desmosome, Pemphigoid is Basement. It helps you recall: Which antigen is attacked in the main blistering diseases.

What does "Pemphigus" stand for?

Desmogleins in desmosomes, intraepidermal split

What does "Pemphigoid" stand for?

BP180 and BP230 at the basement membrane, subepidermal split

What are all the parts of the Pemphigus is Desmosome, Pemphigoid is Basement mnemonic?

Pemphigus: Desmogleins in desmosomes, intraepidermal split; Pemphigoid: BP180 and BP230 at the basement membrane, subepidermal split.

Which topic does this mnemonic belong to?

It belongs to Vesiculobullous disorders in Dermatology.

Where does this mnemonic stop being reliable?

Omits dermatitis herpetiformis and acquired epidermolysis bullosa.

How is this useful clinically?

Predicts blister fragility, Nikolsky sign and immunofluorescence pattern.

How do I make this mnemonic stick?

Say it aloud, write it from memory tomorrow, then again in a week. Then test yourself on a Dermatology question about Vesiculobullous disorders.

Is this a standard mnemonic?

It is a teaching aid written or adapted by our team. Some resemble ones students share informally. Check any fact that matters in a standard source.