The mnemonic
PAT
What each word stands for
- PPhenytoin
- AAspirin at high doses
- TTheophylline
Why it matters clinically
Small dose increases can cause disproportionate rises in level and toxicity.
Where it stops being reliable
Ethanol also follows zero-order kinetics and is not in the acronym; kinetics are dose-dependent, not fixed.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.