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General Surgery · Perioperative care: complications of parenteral nutrition
Sample itemA patient on long-term total parenteral nutrition via a central line develops fever and rigors with no other source. What is the most likely cause, and what is the first step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Catheter-related bloodstream infection; take blood cultures from line and periphery and consider removal
Catheter sepsis is a major TPN complication, with Staphylococcus and Candida the usual organisms. Cultures and line removal if unwell guide treatment. Other complications are hyperglycaemia, refeeding syndrome, cholestasis and fatty liver, and line thrombosis.
Option by option
A. Air embolism; hyperbaric oxygen
Air embolism is acute and does not cause fever and rigors.
B. Cholestasis; stop feeds immediately
Cholestasis is chronic and does not cause rigors.
C. Hyperglycaemia; no action
Hyperglycaemia does not explain rigors.
D. Catheter-related bloodstream infection; take blood cultures from line and periphery and consider removal (correct)
Correct. Suspect line infection with fever and rigors.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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