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Anaesthesia · Critical care: oxygen delivery
Sample itemWhich change produces the largest increase in oxygen delivery in a severely anaemic patient with normal saturation and cardiac output?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Raising the haemoglobin concentration
Oxygen delivery equals cardiac output times arterial oxygen content, and content is mainly haemoglobin times 1.34 times saturation. Dissolved oxygen contributes very little at normal pressures. Raising haemoglobin therefore has the greatest effect when anaemia is the limiting factor.
Option by option
A. Doubling the dissolved oxygen by increasing PaO2
Dissolved oxygen is a minor contributor.
B. Giving a vasodilator
A vasodilator does not increase oxygen content.
C. Raising the haemoglobin concentration (correct)
Correct. Haemoglobin is the major determinant of oxygen content.
D. Reducing the heart rate
Reducing the heart rate would tend to lower cardiac output.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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