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Anatomy · Neuroanatomy: ventricular system and CSF
Sample itemAn 8-month-old infant recovering from bacterial meningitis develops enlarging head size and bulging fontanelle. CT shows dilatation of all ventricles including the fourth. Which mechanism explains this communicating hydrocephalus?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Impaired absorption of CSF at the arachnoid granulations into the superior sagittal sinus
CSF is produced mainly by the choroid plexus and flows through the ventricles and subarachnoid space, being absorbed through arachnoid granulations into the dural venous sinuses, mainly the superior sagittal sinus. Post-meningitic fibrosis of the subarachnoid space and granulations blocks absorption, so all ventricles dilate, including the fourth.
Option by option
A. Impaired absorption of CSF at the arachnoid granulations into the superior sagittal sinus (correct)
Correct. Failure of absorption through the arachnoid granulations causes dilatation of all ventricles.
B. Obstruction of the cerebral aqueduct
Aqueduct obstruction would dilate the lateral and third ventricles but spare the fourth.
C. Overproduction of CSF by the ependymal lining of the central canal
The central canal is not the main CSF source; the choroid plexus is.
D. Blockage of the interventricular foramen by the choroid plexus
Foramen blockage would dilate only the lateral ventricle on that side.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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