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ENT · Head and neck tumours: hypothyroidism after neck radiotherapy
Sample itemA patient treated years ago with radiotherapy to the neck for lymphoma develops fatigue and weight gain. Which investigation is most appropriate?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Serum TSH and free thyroxine
Radiotherapy to the neck commonly causes hypothyroidism, which may appear months to years later, so TSH is monitored regularly in survivors. Early detection allows replacement with levothyroxine. Radiation also increases the long-term risk of thyroid cancer and carotid disease.
Option by option
A. Serum TSH and free thyroxine (correct)
Correct. Thyroid function should be checked.
B. Chest radiograph
A chest radiograph is not relevant to these symptoms.
C. Serum calcium only
Calcium alone does not assess hypothyroidism.
D. Pure tone audiometry
Audiometry is not relevant.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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