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ENT · Nose: Curacao criteria for HHT
Sample itemA 35-year-old has recurrent spontaneous epistaxis, mucocutaneous telangiectasia on the lips and fingertips, and a father with the same problem. How many of the four Curacao criteria does she meet, and what is the diagnostic category?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Three criteria (epistaxis, telangiectasia, family history), so a definite diagnosis of hereditary haemorrhagic telangiectasia
The Curacao criteria are spontaneous recurrent epistaxis, multiple mucocutaneous telangiectasia, visceral arteriovenous lesions and a first-degree relative with the disease. Three or more criteria give a definite diagnosis. Visceral lesions are not yet demonstrated here and need screening.
Option by option
A. All four criteria, including visceral lesions
No visceral lesion has been documented, so the fourth criterion is not yet met.
B. Three criteria (epistaxis, telangiectasia, family history), so a definite diagnosis of hereditary haemorrhagic telangiectasia (correct)
Correct. Three criteria are met, which makes the diagnosis definite.
C. Two criteria, so a possible diagnosis only
Two criteria would be only possible or suspected disease.
D. One criterion, so the diagnosis is unlikely
She clearly meets more than one criterion.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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