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Physiology · Gastrointestinal physiology
Sample itemWhat is the main action of secretin?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Stimulate bicarbonate secretion
Secretin stimulates pancreatic and biliary bicarbonate secretion in response to acidic chyme entering the duodenum, helping neutralize the luminal acid.
Option by option
A. Stimulate gastric acid
Gastrin, not secretin, stimulates gastric acid secretion.
B. Increase insulin resistance
Secretin does not function by increasing insulin resistance.
C. Stimulate bicarbonate secretion (correct)
Correct: secretin promotes bicarbonate-rich secretion.
D. Cause gallbladder contraction
Cholecystokinin is the main hormonal stimulus for gallbladder contraction.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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