Antihypertensives: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Antihypertensives

Sample item

What adverse effect should be monitored with spironolactone?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Hyperkalemia

Spironolactone blocks aldosterone receptors and reduces renal potassium secretion, so serum potassium can rise, especially with renal impairment.

Option by option

  • A. Hyperkalemia (correct)

    Correct: potassium retention can cause hyperkalemia.

  • B. Hypocalcemia

    Calcium is not the principal spironolactone monitoring issue.

  • C. Hypernatremia

    Spironolactone does not classically cause hypernatremia.

  • D. Hypokalemia

    Hypokalemia is more typical of potassium-wasting diuretics.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is A, Hyperkalemia. Spironolactone blocks aldosterone receptors and reduces renal potassium secretion, so serum potassium can rise, especially with renal impairment.

Why is "Hypocalcemia" not the answer?

Calcium is not the principal spironolactone monitoring issue.

Why is "Hypernatremia" not the answer?

Spironolactone does not classically cause hypernatremia.

Why is "Hypokalemia" not the answer?

Hypokalemia is more typical of potassium-wasting diuretics.

What concept does this question test?

It tests Antihypertensives in Pharmacology. The correct option holds because: Correct: potassium retention can cause hyperkalemia.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antihypertensives?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.