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Dermatology · Pigment disorders
Sample itemA patient has sharply demarcated milk-white patches caused by loss of functional melanocytes; which diagnosis best fits?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Depigmented patches from melanocyte loss
Vitiligo produces well-defined depigmented patches because melanocytes are lost or dysfunctional, leaving areas without normal melanin pigment.
Option by option
A. Raised scar tissue
Raised scar tissue is a hypertrophic scar or keloid.
B. Fungal skin infection
Fungal infection commonly produces scale or altered color, not true depigmentation.
C. Bacterial abscess
An abscess is a localized collection of pus.
D. Depigmented patches from melanocyte loss (correct)
Correct: vitiligo reflects loss of melanocyte pigment production.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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