Gastrointestinal physiology: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Gastrointestinal physiology

Sample item

Which stomach cells secrete hydrochloric acid?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Parietal cells

Parietal cells secrete hydrochloric acid and intrinsic factor, creating an acidic environment for protein digestion and supporting vitamin B12 absorption.

Option by option

  • A. Paneth cells

    Paneth cells release antimicrobial peptides in intestinal crypts.

  • B. Goblet cells

    Goblet cells secrete mucus.

  • C. Chief cells

    Chief cells secrete pepsinogen.

  • D. Parietal cells (correct)

    Correct: parietal cells produce gastric acid and intrinsic factor.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is D, Parietal cells. Parietal cells secrete hydrochloric acid and intrinsic factor, creating an acidic environment for protein digestion and supporting vitamin B12 absorption.

Why is "Paneth cells" not the answer?

Paneth cells release antimicrobial peptides in intestinal crypts.

Why is "Goblet cells" not the answer?

Goblet cells secrete mucus.

Why is "Chief cells" not the answer?

Chief cells secrete pepsinogen.

What concept does this question test?

It tests Gastrointestinal physiology in Physiology. The correct option holds because: Correct: parietal cells produce gastric acid and intrinsic factor.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastrointestinal physiology?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.