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Microbiology · Bacteriology
Sample itemWhat virulence factor allows Staphylococcus aureus to bind immunoglobulin Fc portions?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Protein A
Protein A binds the Fc portion of IgG, interfering with opsonization and phagocytosis and contributing to Staphylococcus aureus virulence.
Option by option
A. Flagellum
Flagella provide motility rather than IgG binding.
B. Capsule only
Capsules may impair phagocytosis but do not define this Fc binding.
C. M protein
M protein is a streptococcal virulence factor.
D. Protein A (correct)
Correct: Protein A binds IgG Fc and impairs opsonization.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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