Diuretics: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Diuretics

Sample item

Where do thiazide diuretics act primarily?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Distal convoluted tubule

Thiazides inhibit sodium-chloride transport in the distal convoluted tubule, producing moderate diuresis and increasing calcium reabsorption.

Option by option

  • A. Collecting duct only

    Potassium-sparing drugs act more distally in collecting segments.

  • B. Thick ascending limb

    Loop diuretics act in the thick ascending limb.

  • C. Glomerulus

    Glomerulus filters plasma but is not the thiazide target.

  • D. Distal convoluted tubule (correct)

    Correct: thiazides act in the distal convoluted tubule.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is D, Distal convoluted tubule. Thiazides inhibit sodium-chloride transport in the distal convoluted tubule, producing moderate diuresis and increasing calcium reabsorption.

Why is "Collecting duct only" not the answer?

Potassium-sparing drugs act more distally in collecting segments.

Why is "Thick ascending limb" not the answer?

Loop diuretics act in the thick ascending limb.

Why is "Glomerulus" not the answer?

Glomerulus filters plasma but is not the thiazide target.

What concept does this question test?

It tests Diuretics in Pharmacology. The correct option holds because: Correct: thiazides act in the distal convoluted tubule.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Diuretics?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.