Blood physiology: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Blood physiology

Sample item

Which event initiates primary haemostasis after a vessel injury?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Platelet adhesion to exposed subendothelial collagen via von Willebrand factor

Primary haemostasis begins when platelets adhere to exposed collagen through von Willebrand factor, then activate and aggregate to form a platelet plug.

Option by option

  • A. Production of erythrocytes by bone marrow

    Erythropoiesis does not initiate haemostasis.

  • B. Platelet adhesion to exposed subendothelial collagen via von Willebrand factor (correct)

    Correct: vWF-mediated adhesion starts platelet plug formation.

  • C. Conversion of fibrinogen to fibrin by plasmin

    Fibrin formation belongs to secondary haemostasis.

  • D. Dissolution of the clot by tissue plasminogen activator

    Plasmin-mediated clot dissolution is fibrinolysis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is B, Platelet adhesion to exposed subendothelial collagen via von Willebrand factor. Primary haemostasis begins when platelets adhere to exposed collagen through von Willebrand factor, then activate and aggregate to form a platelet plug.

Why is "Production of erythrocytes by bone marrow" not the answer?

Erythropoiesis does not initiate haemostasis.

Why is "Conversion of fibrinogen to fibrin by plasmin" not the answer?

Fibrin formation belongs to secondary haemostasis.

Why is "Dissolution of the clot by tissue plasminogen activator" not the answer?

Plasmin-mediated clot dissolution is fibrinolysis.

What concept does this question test?

It tests Blood physiology in Physiology. The correct option holds because: Correct: vWF-mediated adhesion starts platelet plug formation.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Blood physiology?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.