Wound healing: practice question

A General Surgery question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Surgery · Wound healing

Sample item

Which vitamin deficiency most directly impairs collagen hydroxylation and can delay wound healing?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Vitamin C deficiency

Vitamin C is required for hydroxylation of proline and lysine during collagen synthesis. Deficiency causes defective connective tissue formation and poor wound healing.

Option by option

  • A. Vitamin K deficiency

    Vitamin K deficiency primarily impairs activation of clotting factors.

  • B. Vitamin C deficiency (correct)

    Correct. Ascorbate is an essential cofactor in collagen maturation.

  • C. Vitamin D deficiency

    Vitamin D deficiency affects bone mineralization rather than collagen hydroxylation.

  • D. Vitamin B12 deficiency

    Vitamin B12 deficiency causes megaloblastic anemia and neurologic dysfunction.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More General Surgery questions

Questions about this General Surgery question

What is the answer to this General Surgery question?

The best answer is B, Vitamin C deficiency. Vitamin C is required for hydroxylation of proline and lysine during collagen synthesis.

Why is "Vitamin K deficiency" not the answer?

Vitamin K deficiency primarily impairs activation of clotting factors.

Why is "Vitamin D deficiency" not the answer?

Vitamin D deficiency affects bone mineralization rather than collagen hydroxylation.

Why is "Vitamin B12 deficiency" not the answer?

Vitamin B12 deficiency causes megaloblastic anemia and neurologic dysfunction.

What concept does this question test?

It tests Wound healing in General Surgery. Deficiency causes defective connective tissue formation and poor wound healing.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Wound healing?

Learn classic signs and eponyms alongside what they diagnose. Then use the flashcards and the other General Surgery questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.