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Pharmacology · Anaesthesia drugs
Sample itemWhat is the emergency treatment principle for malignant hyperthermia?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Stop triggering agent and give dantrolene
Malignant hyperthermia requires immediate discontinuation of triggering anaesthetic, dantrolene, active cooling, and treatment of hyperkalaemia and acidosis.
Option by option
A. Give succinylcholine again
Succinylcholine can trigger the crisis.
B. Stop triggering agent and give dantrolene (correct)
Correct: dantrolene directly treats uncontrolled calcium release.
C. Delay treatment until CK result
Treatment cannot wait for laboratory confirmation.
D. Use only oral antihistamine
Antihistamine does not address muscle hypermetabolism.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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