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Dermatology · Acne
Sample itemA teenager has comedones, papules, pustules, and nodules on the face and back. Which lesion is most specific for acne vulgaris?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Comedone
Acne vulgaris involves follicular plugging and inflammation; open or closed comedones are the defining primary lesion. Severity and scarring risk guide topical, systemic, and referral treatment.
Option by option
A. Wheal
Wheals are transient edematous lesions of urticaria.
B. Purpura
Purpura reflects extravasated blood.
C. Comedone (correct)
Correct. Comedones distinguish acne from many other inflammatory eruptions.
D. Vesicle
Vesicles contain clear fluid and occur in viral and eczematous conditions.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.