Try it
General Surgery · Wound healing
Sample itemWhich nutrient deficiency particularly impairs collagen hydroxylation and wound healing?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Vitamin C deficiency
Vitamin C is required for proline and lysine hydroxylation during collagen synthesis. Deficiency causes poor wound healing and fragile capillaries.
Option by option
A. Vitamin D excess
Vitamin D excess is not the collagen-hydroxylation defect.
B. Vitamin B12 deficiency
B12 deficiency causes megaloblastic anaemia and neuropathy.
C. Vitamin K excess
Vitamin K is involved in coagulation-factor carboxylation.
D. Vitamin C deficiency (correct)
Correct. Ascorbate is essential for stable collagen formation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.