Gastrointestinal microbiology: practice question

A Microbiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Microbiology · Gastrointestinal microbiology

Sample item

Which organism causes cholera through enterotoxin-mediated chloride secretion?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Vibrio cholerae

Vibrio cholerae toxin increases intestinal cyclic AMP, driving chloride and water secretion and causing profuse watery diarrhoea.

Option by option

  • A. Yersinia pestis

    Yersinia pestis causes plague.

  • B. Shigella dysenteriae

    Shigella causes invasive dysentery.

  • C. Vibrio cholerae (correct)

    Correct: cholera toxin causes secretory fluid loss.

  • D. Salmonella Typhi

    Typhi causes enteric fever.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Microbiology questions

Questions about this Microbiology question

What is the answer to this Microbiology question?

The best answer is C, Vibrio cholerae. Vibrio cholerae toxin increases intestinal cyclic AMP, driving chloride and water secretion and causing profuse watery diarrhoea.

Why is "Yersinia pestis" not the answer?

Yersinia pestis causes plague.

Why is "Shigella dysenteriae" not the answer?

Shigella causes invasive dysentery.

Why is "Salmonella Typhi" not the answer?

Typhi causes enteric fever.

What concept does this question test?

It tests Gastrointestinal microbiology in Microbiology. The correct option holds because: Correct: cholera toxin causes secretory fluid loss.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastrointestinal microbiology?

Make a one-line identity card for each organism: shape and stain, defining test, toxin, disease and drug. Then use the flashcards and the other Microbiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.