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Microbiology · Virology
Sample itemWhich hepatitis virus requires hepatitis B surface antigen for replication?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Hepatitis D virus
Hepatitis D virus is a defective RNA virus that requires hepatitis B surface antigen to assemble infectious particles and propagate.
Option by option
A. Hepatitis A virus
HAV is independent faecal-oral virus.
B. Hepatitis C virus
HCV is independent RNA virus.
C. Hepatitis E virus
HEV does not require HBV.
D. Hepatitis D virus (correct)
Correct: HDV depends on HBV surface antigen.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.