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Microbiology · Bacteriology
Sample itemA pregnant woman develops fever and diarrhoea after eating unpasteurised soft cheese. Her newborn develops meningitis. Gram stain of CSF shows small Gram-positive rods that show tumbling motility at room temperature. What is the organism?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Listeria monocytogenes
Listeria monocytogenes is a motile Gram-positive bacillus that grows at refrigeration temperature (cold enrichment), shows tumbling motility at 25 degrees C and causes neonatal meningitis and sepsis after maternal infection from contaminated dairy products. Ampicillin is a key drug.
Option by option
A. Corynebacterium diphtheriae
Corynebacterium diphtheriae is non-motile and causes pharyngeal pseudomembrane.
B. Clostridium perfringens
Clostridium perfringens is non-motile and causes gas gangrene and food poisoning.
C. Listeria monocytogenes (correct)
Correct. Tumbling motility, cold growth and dairy exposure point to Listeria.
D. Bacillus cereus
Bacillus cereus causes food poisoning from rice and is a larger rod that forms spores.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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