Uveitis: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Uveitis

Sample item

Three weeks after a penetrating injury to his right eye, a 25-year-old develops pain, photophobia and reduced vision in the uninjured left eye as well. Histology of the injured eye shows granulomatous inflammation with Dalen-Fuchs nodules. What is the diagnosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Sympathetic ophthalmia

Sympathetic ophthalmia is a bilateral granulomatous panuveitis following penetrating trauma or surgery to one eye, caused by an autoimmune reaction against uveal antigens. Dalen-Fuchs nodules are characteristic, and early enucleation of a blind injured eye can prevent it, while steroids and immunosuppressants treat established disease.

Option by option

  • A. Endophthalmitis of the left eye

    Endophthalmitis is infective and does not appear in the other, uninjured eye.

  • B. Sympathetic ophthalmia (correct)

    Correct. Bilateral granulomatous uveitis after trauma with Dalen-Fuchs nodules defines it.

  • C. Fuchs heterochromic iridocyclitis

    Fuchs heterochromic iridocyclitis is a chronic unilateral, mild uveitis without synechiae and without a history of trauma.

  • D. Phacoanaphylactic uveitis

    Phacoanaphylactic uveitis is a response to lens protein in the same eye.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is B, Sympathetic ophthalmia. Sympathetic ophthalmia is a bilateral granulomatous panuveitis following penetrating trauma or surgery to one eye, caused by an autoimmune reaction against uveal antigens.

Why is "Endophthalmitis of the left eye" not the answer?

Endophthalmitis is infective and does not appear in the other, uninjured eye.

Why is "Fuchs heterochromic iridocyclitis" not the answer?

Fuchs heterochromic iridocyclitis is a chronic unilateral, mild uveitis without synechiae and without a history of trauma.

Why is "Phacoanaphylactic uveitis" not the answer?

Phacoanaphylactic uveitis is a response to lens protein in the same eye.

What concept does this question test?

It tests Uveitis in Ophthalmology. Dalen-Fuchs nodules are characteristic, and early enucleation of a blind injured eye can prevent it, while steroids and immunosuppressants treat established disease.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Uveitis?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.