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Anaesthesia · Resuscitation: shockable rhythms
Sample itemDuring a cardiac arrest, ventricular fibrillation persists after three defibrillation shocks and adrenaline. Which antiarrhythmic drug is recommended next?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Amiodarone 300 mg intravenously
In refractory ventricular fibrillation or pulseless ventricular tachycardia, amiodarone 300 mg is given after the third shock, with a further 150 mg dose after the fifth shock if needed. High-quality CPR continues with minimal interruptions, and reversible causes (the 4 Hs and 4 Ts) are sought. Lidocaine is an alternative when amiodarone is unavailable. Atropine is no longer recommended in asystole or pulseless electrical activity.
Option by option
A. Amiodarone 300 mg intravenously (correct)
Correct. Amiodarone is the recommended drug for shock-refractory VF or pulseless VT.
B. Atropine 3 mg
Atropine has no role in the treatment of VF.
C. Calcium chloride
Calcium is given only in specific situations such as hyperkalaemia.
D. Adenosine 6 mg
Adenosine treats supraventricular tachycardia, not ventricular fibrillation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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