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Microbiology · Bacteriology: streptococci
Sample itemA throat swab culture grows Gram-positive cocci in chains with a wide zone of clear (beta) haemolysis on blood agar. The organism is sensitive to bacitracin and PYR positive. Which organism is this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Streptococcus pyogenes (Group A)
Group A streptococcus is beta-haemolytic, bacitracin-sensitive and PYR positive. It causes pharyngitis, skin infection, and the non-suppurative sequelae rheumatic fever and post-streptococcal glomerulonephritis. Group B is bacitracin-resistant and hippurate positive. Enterococcus is PYR positive but bacitracin-resistant and non-beta-haemolytic.
Option by option
A. Streptococcus pyogenes (Group A) (correct)
Correct. This combination identifies Group A streptococcus.
B. Enterococcus faecalis
Enterococcus grows in 6.5% sodium chloride and is not usually beta-haemolytic.
C. Streptococcus pneumoniae
Pneumococcus is alpha-haemolytic and optochin sensitive.
D. Streptococcus agalactiae (Group B)
Group B streptococcus is bacitracin resistant, hippurate positive and CAMP positive.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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