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Microbiology · Virology: chikungunya
Sample itemA 45-year-old woman has fever, rash and severe symmetric small-joint pain after a mosquito season. Joint pain persists for months despite resolution of fever. Which statement about the causative agent is correct?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. An alphavirus transmitted by Aedes mosquitoes, with arthralgia that may persist for months
Chikungunya virus is a togavirus of the alphavirus genus spread by Aedes aegypti and Aedes albopictus. The name means that which bends up, from the stooped posture caused by severe polyarthralgia, which can last for months. Haemorrhage and shock are uncommon, unlike in dengue.
Option by option
A. A flavivirus transmitted by Anopheles mosquitoes, with cerebral involvement
Anopheles is the vector of malaria parasites, not of chikungunya virus, which is an alphavirus spread by Aedes.
B. A flavivirus transmitted by Culex mosquitoes, with hepatic necrosis
Culex-borne flavivirus with hepatic necrosis does not match this illness.
C. A bunyavirus transmitted by ticks, with haemorrhage
Tick-borne bunyavirus illnesses cause haemorrhagic fever rather than chronic polyarthralgia.
D. An alphavirus transmitted by Aedes mosquitoes, with arthralgia that may persist for months (correct)
Correct. Aedes-borne alphavirus with prolonged arthralgia describes chikungunya.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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