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Microbiology · Virology: Nipah virus
Sample itemIn an endemic region of South Asia, several people develop fever, headache, drowsiness and respiratory distress after one patient drank raw palm sap. Which source is most likely for the index case?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Contamination of the sap by fruit bats
Nipah virus is a paramyxovirus whose natural reservoir is fruit bats of the genus Pteropus. Humans acquire it from bat-contaminated food such as raw date palm sap or fruit, or from infected animals, and then spread it to close contacts. Encephalitis and respiratory disease are major features, and strict infection control is needed.
Option by option
A. Contaminated ticks on cattle
Ticks transmit Kyasanur forest disease and Crimean-Congo fever.
B. Contamination of the sap with rodent urine
Rodents are the source of arenaviruses such as Lassa and not of Nipah.
C. Contamination of the sap by fruit bats (correct)
Correct. Fruit bats contaminate raw sap or fruit with saliva and urine.
D. Bite of Aedes mosquitoes breeding in water containers
Aedes mosquitoes transmit dengue and chikungunya and not Nipah.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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