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Microbiology · Mycology: tinea incognito
Sample itemA 30-year-old man has extensive, itchy, ring-shaped lesions on the groin and trunk that have lost their raised scaly border after months of using an over-the-counter steroid and antifungal combination cream. What is the most appropriate initial investigation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. KOH mount of scrapings from the lesion edge
Topical steroids suppress inflammation and alter the appearance of dermatophytosis, producing tinea incognito with extensive spread. Direct microscopy of scrapings in 10 to 20% potassium hydroxide shows septate hyphae and confirms the diagnosis, and culture on Sabouraud agar identifies the species. Treatment is with oral antifungals once steroid use stops.
Option by option
A. Patch testing with standard allergens
Patch testing assesses contact allergy and does not diagnose fungal infection.
B. Tzanck smear from a lesion
A Tzanck smear detects multinucleated giant cells in herpesvirus infection.
C. KOH mount of scrapings from the lesion edge (correct)
Scrapings in KOH show hyphae quickly and cheaply and confirm dermatophytosis.
D. Wood's lamp examination of the lesions
Most dermatophytes of the body and groin do not fluoresce, so Wood's lamp is of little value here.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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