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General Surgery · Urology: priapism
Sample itemA 22-year-old man with sickle cell disease has had a painful rigid erection for 8 hours. The glans is soft. Cavernosal blood gas shows a dark blood with pH 7.0 and low oxygen. What is the next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Aspiration of the corpora with intracavernosal phenylephrine
Ischaemic (low-flow) priapism is a compartment syndrome of the penis and an emergency, since irreversible erectile dysfunction follows after about 24 hours. Treatment is stepwise: analgesia, corporal aspiration with saline irrigation and intracavernosal alpha-agonist (phenylephrine), then shunting if this fails. Sickle cell disease is a common cause, and hydration, oxygen and exchange transfusion may be added.
Option by option
A. Immediate distal shunt without aspiration
Surgery is escalated to only if aspiration and injection fail.
B. Aspiration of the corpora with intracavernosal phenylephrine (correct)
Decompressing the corpora and causing vasoconstriction restores venous outflow.
C. Oral sildenafil
Phosphodiesterase inhibitors promote erection and could worsen the condition.
D. Application of cold packs and analgesia alone
Conservative measures alone rarely resolve established ischaemic priapism after several hours.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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