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General Surgery · Urology: post-obstructive diuresis
Sample itemA 72-year-old man with chronic urinary retention has 2.5 litres drained after catheterisation. Next morning his urine output is 400 mL per hour, and he is thirsty, with postural hypotension. What is the most appropriate management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Monitor urine output and electrolytes and replace losses with intravenous fluids
After relief of chronic high-pressure retention, some patients develop a post-obstructive diuresis from a retained solute and urea load and temporary tubular concentrating defect. It is usually self-limiting but can cause dehydration, hypokalaemia and hypotension. Management is close monitoring with intravenous replacement of fluid and electrolyte losses, avoiding over-replacement that sustains the diuresis.
Option by option
A. Intravenous furosemide
A diuretic would worsen volume depletion in a patient already diuresing.
B. Clamp the catheter to stop the diuresis
Clamping the catheter would re-obstruct the bladder and risk renal damage.
C. Desmopressin
Desmopressin is for diabetes insipidus and is not appropriate for an osmotic diuresis.
D. Monitor urine output and electrolytes and replace losses with intravenous fluids (correct)
Titrated fluid and electrolyte replacement prevents hypovolaemia while the kidney recovers.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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