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Forensic Medicine · Identification: ABO grouping in disputed paternity
Sample itemIn a disputed paternity case the mother is group A and her child is group O. The alleged father is group AB. What can be concluded from the ABO grouping?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. He is excluded, since a group AB man cannot transmit an O allele
A group O child is homozygous for the O allele and must receive one O allele from each parent. A group AB man has only A and B alleles and cannot give an O allele, so he is excluded. Blood grouping can only exclude paternity and cannot prove it.
Option by option
A. He is excluded, since a group AB man cannot transmit an O allele (correct)
Correct. An AB man has no O allele to pass to a group O child.
B. He is not excluded, since an AB man can transmit either A or B to a group O child
A or B alleles would give a child of group A, B or AB, never group O.
C. He is not excluded, since the mother is group A
The mother being group A does not matter, because the father still has to supply an O allele.
D. The grouping cannot be interpreted without Rh typing
Rh typing is independent of the ABO system and does not change this exclusion.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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