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Microbiology · Bacteriology: Moraxella catarrhalis
Sample itemA 65-year-old with COPD has an acute exacerbation. Sputum Gram stain shows kidney-bean shaped Gram-negative diplococci. The isolate is oxidase positive, produces beta-lactamase and ferments no sugars. Which organism is it?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Moraxella catarrhalis
Moraxella catarrhalis is an oxidase-positive Gram-negative diplococcus that does not ferment sugars, is usually beta-lactamase positive and causes otitis media, sinusitis and COPD exacerbations. Neisseria species can be separated from it by their sugar fermentation.
Option by option
A. Neisseria meningitidis
N. meningitidis ferments glucose and maltose.
B. Haemophilus influenzae
H. influenzae is a coccobacillus needing X and V factors, not a diplococcus.
C. Acinetobacter baumannii
A. baumannii is an oxidase-negative coccobacillus linked to ventilator-associated pneumonia.
D. Moraxella catarrhalis (correct)
Correct. A non-saccharolytic oxidase-positive diplococcus with beta-lactamase is M. catarrhalis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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