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Radiology · Neuroimaging: retinoblastoma
Sample itemA 2-year-old has leukocoria. Which imaging finding best separates retinoblastoma from Coats disease?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Intraocular calcification within the mass
Calcification within an intraocular mass on ultrasound or CT is the hallmark of retinoblastoma, while MRI is preferred to avoid radiation, especially in the hereditary form. Coats disease shows exudate and detachment without calcification. A small globe with a stalk indicates persistent fetal vasculature.
Option by option
A. A small globe with a retrolental stalk
A small globe with a retrolental stalk indicates persistent fetal vasculature.
B. Subretinal exudate with retinal detachment
Subretinal exudate and detachment are features of Coats disease.
C. Intraocular calcification within the mass (correct)
Correct. Calcification in the mass is typical for retinoblastoma and absent in Coats.
D. Peripheral retinal neovascularisation in a premature infant
Neovascularisation in a premature infant indicates retinopathy of prematurity.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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