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ENT · Larynx and airway: fatigable voice of myasthenia
Sample itemA 30-year-old teacher's voice becomes weak and breathy after prolonged speaking and recovers after rest. She has evening ptosis. Laryngoscopy at rest is normal. What is the likely cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Myasthenia gravis
Fatigable weakness that worsens with use and improves with rest, with ocular signs, indicates a neuromuscular junction disorder. Laryngeal myasthenia may present as voice fatigue, so acetylcholine receptor antibodies and repetitive stimulation are indicated.
Option by option
A. Adductor spasmodic dysphonia
Spasmodic dysphonia gives strained, strangled voice with spasms, not fatigue.
B. Myasthenia gravis (correct)
Correct. Use-related fatigue with ptosis points to myasthenia gravis.
C. Vocal nodules
Nodules cause persistent hoarseness with visible lesions on the folds.
D. Muscle tension dysphonia
Muscle tension dysphonia shows hyperfunction and not ptosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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