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General Medicine · Gastroenterology and hepatology: Zenker diverticulum
Sample itemA 70-year-old man has dysphagia, regurgitation of undigested food hours after eating, halitosis and a gurgling sound in the neck. A barium swallow shows a posterior outpouching at the level of the cricoid cartilage. Which abnormality underlies this condition?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Incomplete relaxation of the cricopharyngeus
Zenker diverticulum is a pulsion pouch through Killian triangle above the cricopharyngeus. Poor coordination or incomplete relaxation of the cricopharyngeus raises hypopharyngeal pressure during swallowing. Treatment is by cricopharyngeal myotomy with diverticulotomy or diverticulectomy.
Option by option
A. Loss of myenteric neurons in the oesophageal body
Loss of myenteric neurons in the oesophageal body causes achalasia, not an upper pouch.
B. Herniation of the gastric fundus through the hiatus
Fundal herniation describes a hiatus hernia, which does not cause a neck pouch.
C. Incomplete relaxation of the cricopharyngeus (correct)
Correct. Poor relaxation of the cricopharyngeus pushes mucosa out through Killian triangle.
D. Failed relaxation of the lower oesophageal sphincter
Failure of the lower sphincter to relax describes achalasia, with a bird-beak lower oesophagus.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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