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General Medicine · Gastroenterology and hepatology: hepatocellular adenoma
Sample itemA 28-year-old woman on long-term combined oral contraceptive pills presents with sudden severe right upper quadrant pain and hypotension. CT shows a 7 cm liver mass with haemorrhage inside and around it. What is the underlying lesion?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Hepatocellular adenoma
Hepatocellular adenoma is linked to oestrogen exposure and may rupture or bleed, particularly when it exceeds 5 cm. Management includes stopping hormones, and resection for large lesions. Focal nodular hyperplasia rarely bleeds.
Option by option
A. Focal nodular hyperplasia
Focal nodular hyperplasia rarely bleeds and is not oestrogen driven.
B. Hepatocellular adenoma (correct)
Correct. An oestrogen-related lesion over 5 cm that bleeds is typical of adenoma.
C. Cavernous haemangioma
Haemangiomas rarely rupture spontaneously.
D. Hepatic hydatid cyst
A hydatid cyst occurs after exposure to dogs and sheep and shows daughter cysts.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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