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General Medicine · Cardiology: squatting in tetralogy of Fallot
Sample itemA child with tetralogy of Fallot squats during play and the cyanosis eases. What is the physiological basis of this relief?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Higher systemic resistance reduces right-to-left shunting
Squatting kinks the femoral arteries and raises systemic vascular resistance, so less blood is shunted right-to-left across the ventricular septal defect and more goes to the lungs. Venous return of poorly saturated blood from the legs is also reduced.
Option by option
A. Larger venous return widens the infundibular obstruction
Increased venous return would worsen infundibular spasm and does not relieve cyanosis.
B. Slower heart rate lengthens ventricular filling time
Heart rate is not the mechanism; relief comes from the change in systemic resistance.
C. Lower pulmonary resistance raises pulmonary flow directly
Squatting does not lower pulmonary resistance; the benefit comes from the systemic side.
D. Higher systemic resistance reduces right-to-left shunting (correct)
Correct. Raised systemic resistance favours flow to the lungs and lowers the right-to-left shunt.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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