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General Medicine · Emergency and critical care: alcohol withdrawal delirium
Sample itemA chronic heavy drinker is admitted after a fall. Three days after his last drink he becomes agitated, disoriented, has coarse tremor, sweating, tachycardia and vivid visual hallucinations. What is the diagnosis and first-line drug?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Delirium tremens treated with a benzodiazepine
Delirium tremens appears 48 to 96 hours after the last drink, with autonomic hyperactivity, tremor and hallucinations. Benzodiazepines are first line, with thiamine given before glucose.
Option by option
A. Alcoholic hallucinosis treated with phenytoin
Alcoholic hallucinosis occurs with clear consciousness and no autonomic storm.
B. Wernicke encephalopathy treated with haloperidol
Wernicke encephalopathy features ophthalmoplegia and ataxia, and antipsychotics lower the seizure threshold.
C. Delirium tremens treated with a benzodiazepine (correct)
Correct. Benzodiazepines treat withdrawal and prevent seizures.
D. Hepatic encephalopathy treated with lactulose alone
Hepatic encephalopathy does not explain the autonomic storm after abstinence.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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