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Physiology · Renal and acid–base: bladder storage phase
Sample itemDuring the storage phase of the bladder, sympathetic activity through the hypogastric nerve (T10 to L2) helps continence. Which combination of effects does it produce?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Detrusor relaxation and contraction of the internal urethral sphincter
In the storage phase, sympathetic fibres relax the detrusor through beta-3 receptors and contract the bladder neck and internal sphincter through alpha-1 receptors. The external sphincter, a striated muscle supplied by the pudendal nerve, is under voluntary control. Voiding needs parasympathetic detrusor contraction.
Option by option
A. Detrusor contraction and relaxation of the internal urethral sphincter
Detrusor contraction with sphincter relaxation is the parasympathetic voiding pattern.
B. Detrusor contraction and contraction of the external urethral sphincter
Detrusor contraction would produce voiding, and the external sphincter is a somatic structure.
C. Detrusor relaxation and contraction of the internal urethral sphincter (correct)
Correct. Sympathetic action favours storage by relaxing the detrusor and closing the internal sphincter.
D. Detrusor relaxation and relaxation of the external urethral sphincter
The external sphincter is somatic and is not relaxed by sympathetic nerves; relaxing it would favour voiding.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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