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Anatomy · Neuroanatomy: hypothalamic thermoregulation
Sample itemAfter surgery near the base of the brain, a patient cannot dissipate heat and becomes hyperthermic in a warm room, with absent sweating and cutaneous vasodilation. Which hypothalamic region is damaged?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Preoptic and anterior hypothalamus
The preoptic and anterior hypothalamus senses a rise in temperature and triggers sweating and vasodilation. The posterior hypothalamus drives heat conservation and production, so its damage causes failure to respond to cold.
Option by option
A. Lateral hypothalamic area
The lateral hypothalamic area is the feeding centre.
B. Ventromedial nucleus
The ventromedial nucleus is the satiety centre.
C. Posterior hypothalamus
Posterior hypothalamic damage impairs heat conservation, so the patient is poikilothermic in the cold.
D. Preoptic and anterior hypothalamus (correct)
Correct. Anterior hypothalamic damage abolishes heat-loss responses and causes hyperthermia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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