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Anaesthesia · Premedication: hyoscine
Sample itemWhich premedicant produces sedation, amnesia and an antisialogogue effect together?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Hyoscine (scopolamine)
Hyoscine crosses the blood-brain barrier and causes sedation and amnesia in addition to drying secretions and an antiemetic effect. It can cause delirium in the elderly.
Option by option
A. Metoclopramide
Metoclopramide is a prokinetic and antiemetic without amnesia.
B. Glycopyrrolate
Glycopyrrolate has no central action.
C. Ranitidine
Ranitidine reduces gastric acid only.
D. Hyoscine (scopolamine) (correct)
Correct. Hyoscine has central sedative and amnestic effects.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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