Complications: anaphylaxis cause: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Complications: anaphylaxis cause

Sample item

Which group of drugs is the most common cause of perioperative anaphylaxis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Neuromuscular blocking agents

Neuromuscular blockers, mainly suxamethonium and rocuronium, are the leading cause in most classical series (about 50 to 60% in older European data), with latex and antibiotics next; some recent national audits rank antibiotics first. The quaternary ammonium group is the epitope.

Option by option

  • A. Neuromuscular blocking agents (correct)

    Correct. Relaxants are the leading cause.

  • B. Inhalational agents

    Volatile agents rarely cause it.

  • C. Local anaesthetics

    Local anaesthetics rarely cause it.

  • D. Opioids

    Opioids rarely cause true anaphylaxis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is A, Neuromuscular blocking agents. Neuromuscular blockers, mainly suxamethonium and rocuronium, are the leading cause in most classical series (about 50 to 60% in older European data), with latex and antibiotics next; some recent national audits rank antibiotics first.

Why is "Inhalational agents" not the answer?

Volatile agents rarely cause it.

Why is "Local anaesthetics" not the answer?

Local anaesthetics rarely cause it.

Why is "Opioids" not the answer?

Opioids rarely cause true anaphylaxis.

What concept does this question test?

It tests Complications: anaphylaxis cause in Anaesthesia. The quaternary ammonium group is the epitope.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Complications: anaphylaxis cause?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.