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ENT · Oral cavity: verrucous carcinoma
Sample itemA tobacco chewer has a slow-growing, exophytic, warty white lesion of the buccal mucosa with a broad pushing base and no nodal disease. Biopsy shows well-differentiated squamous epithelium. What is it called?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Verrucous carcinoma (Ackerman's tumour)
Verrucous carcinoma is a low-grade variant of squamous carcinoma with a pushing border, rarely metastasising. Wide local excision is the treatment, and radiotherapy is avoided as it may cause anaplastic transformation.
Option by option
A. Spindle cell carcinoma
Spindle cell carcinoma is a sarcomatoid variant.
B. Adenoid squamous carcinoma
Adenoid squamous carcinoma is rare and aggressive.
C. Basaloid carcinoma
Basaloid carcinoma is an aggressive variant.
D. Verrucous carcinoma (Ackerman's tumour) (correct)
Correct. Verrucous carcinoma matches the description.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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