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ENT · Head and neck: extranodal extension
Sample itemAfter surgery for oral cavity carcinoma, histology shows extranodal extension in the neck nodes and a close margin. What is the usual adjuvant treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Postoperative concurrent chemoradiotherapy with cisplatin
Extranodal extension and positive margins are high-risk features, and adjuvant concurrent cisplatin-based chemoradiotherapy improves locoregional control and survival. Radioiodine is for differentiated thyroid cancer.
Option by option
A. Postoperative concurrent chemoradiotherapy with cisplatin (correct)
Correct. Chemoradiotherapy is the standard for these features.
B. Radioiodine
Radioiodine is not for squamous carcinoma.
C. Hormone therapy
Hormone therapy is not used.
D. Observation
Observation risks recurrence.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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