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Orthopaedics · Bone infection: Marjolin ulcer
Sample itemA man with a chronic discharging sinus from osteomyelitis of the tibia for 25 years develops a non-healing ulcer with everted edges. Which complication is suspected?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Squamous cell carcinoma (Marjolin ulcer)
Squamous cell carcinoma can arise in long-standing sinuses, burn scars and chronic ulcers (Marjolin ulcer). A change in character of the discharge or the edge warrants a biopsy, and treatment is wide excision or amputation.
Option by option
A. Squamous cell carcinoma (Marjolin ulcer) (correct)
Correct. Long-standing sinuses can transform into squamous cell carcinoma.
B. Amyloidosis only
Amyloidosis is a systemic complication but does not cause an ulcer with everted edges.
C. Melanoma
Melanoma is not typical here.
D. Basal cell carcinoma
Basal cell carcinoma is not typical for chronic sinus tracts.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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