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Radiology · Chest imaging: sarcoidosis
Sample itemA young woman has a chest radiograph with symmetrical bilateral hilar enlargement and right paratracheal nodes, and is otherwise well apart from erythema nodosum. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Sarcoidosis (Lofgren syndrome)
Symmetrical bilateral hilar lymphadenopathy with erythema nodosum and arthralgia is Lofgren syndrome, a good-prognosis form of sarcoidosis. The right paratracheal node enlargement is described as a 1-2-3 sign. Unilateral or asymmetrical adenopathy would favour lymphoma or tuberculosis.
Option by option
A. Bronchogenic carcinoma
Carcinoma presents with a unilateral hilar mass.
B. Lymphoma
Lymphoma is usually asymmetric and with systemic symptoms.
C. Primary tuberculosis
Primary TB tends to cause unilateral hilar adenopathy.
D. Sarcoidosis (Lofgren syndrome) (correct)
Correct. Bilateral symmetrical hilar nodes with erythema nodosum suggest sarcoidosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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