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Radiology · Chest imaging: Pneumocystis pneumonia
Sample itemA patient with advanced HIV has dyspnoea and hypoxia. A chest radiograph is near normal, but HRCT shows extensive bilateral perihilar ground glass opacities. What is the most likely infection?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Pneumocystis jirovecii pneumonia
PJP typically shows bilateral perihilar ground glass opacities on CT, often with cysts (pneumatoceles) and relative peripheral sparing. A normal radiograph does not exclude it. Cotrimoxazole is the treatment of choice.
Option by option
A. Lobar pneumococcal pneumonia
Pneumococcal pneumonia is lobar and not typically diffuse ground glass.
B. Aspergilloma
Aspergilloma forms a mass within a pre-existing cavity.
C. Pneumocystis jirovecii pneumonia (correct)
Correct. Bilateral perihilar ground glass in advanced HIV suggests PJP.
D. Lung abscess from anaerobes
Lung abscess shows a cavity with an air-fluid level.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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