Cardiology: hypertension in pregnancy: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Medicine · Cardiology: hypertension in pregnancy

Sample item

A 28-year-old woman at 30 weeks of gestation has a blood pressure of 170/110 mmHg. Which antihypertensive must be avoided?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Enalapril

ACE inhibitors and angiotensin receptor blockers are contraindicated in pregnancy because they cause fetal renal dysgenesis, oligohydramnios, skull hypoplasia and neonatal renal failure. Labetalol, methyldopa and nifedipine are the usual safe agents. Magnesium sulfate is added for severe pre-eclampsia.

Option by option

  • A. Methyldopa

    Methyldopa has a long safety record in pregnancy.

  • B. Labetalol

    Labetalol is a standard safe choice in pregnancy.

  • C. Enalapril (correct)

    Correct. ACE inhibitors are fetotoxic and contraindicated.

  • D. Nifedipine

    Nifedipine is an accepted first-line agent.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is C, Enalapril. ACE inhibitors and angiotensin receptor blockers are contraindicated in pregnancy because they cause fetal renal dysgenesis, oligohydramnios, skull hypoplasia and neonatal renal failure.

Why is "Methyldopa" not the answer?

Methyldopa has a long safety record in pregnancy.

Why is "Labetalol" not the answer?

Labetalol is a standard safe choice in pregnancy.

Why is "Nifedipine" not the answer?

Nifedipine is an accepted first-line agent.

What concept does this question test?

It tests Cardiology: hypertension in pregnancy in General Medicine. Labetalol, methyldopa and nifedipine are the usual safe agents. Magnesium sulfate is added for severe pre-eclampsia.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Cardiology: hypertension in pregnancy?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.