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General Surgery · Thyroid: Riedel thyroiditis
Sample itemA woman has a woody-hard, fixed thyroid with dysphagia and dyspnoea that mimics anaplastic carcinoma. Biopsy shows dense fibrosis without malignant cells. Which diagnosis fits?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Riedel thyroiditis
Riedel thyroiditis is a rare IgG4-related fibrosing disorder, in which fibrosis extends beyond the capsule into neck structures. Surgery is limited to isthmusectomy for relief of compression, while steroids and tamoxifen may help. Biopsy is essential to exclude carcinoma.
Option by option
A. Graves disease
Graves disease is diffusely enlarged and hyperthyroid.
B. Papillary carcinoma
Papillary carcinoma would show malignant cells.
C. Riedel thyroiditis (correct)
Correct. Woody-hard fibrosis with no malignancy defines Riedel thyroiditis.
D. De Quervain thyroiditis
De Quervain thyroiditis is painful and self-limiting.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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