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General Medicine · Infectious diseases
Sample itemWhat is the standard treatment of uncomplicated Plasmodium falciparum malaria in India?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Artemisinin-based combination therapy
Artemisinin-based combinations are recommended because of widespread chloroquine resistance in falciparum malaria. The specific partner drug follows national guidelines for the region. Primaquine is added to clear gametocytes. Chloroquine alone remains used for vivax in many areas.
Option by option
A. Primaquine alone
Primaquine does not kill the blood stages and is used as a gametocidal or radical-cure agent.
B. Artemisinin-based combination therapy (correct)
Correct. Artemisinin rapidly clears parasites and the partner drug prevents resistance.
C. Chloroquine alone
Chloroquine resistance is widespread in falciparum malaria.
D. Quinine alone
Quinine is reserved for specific situations such as the first trimester or when ACT is unavailable.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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