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ENT · Ear and audiology: Paget disease of the temporal bone
Sample itemA 68-year-old man has bone pain, an increasing hat size and a raised serum alkaline phosphatase. He has progressive bilateral mixed hearing loss. What is the underlying diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Paget disease of bone
Paget disease of the temporal bone causes sensorineural loss from cochlear involvement and conductive loss from ossicular fixation, giving a mixed pattern. The raised alkaline phosphatase with normal calcium and enlarging skull clinch the diagnosis. Bisphosphonates are used.
Option by option
A. Otosclerosis
Otosclerosis occurs in younger adults with normal alkaline phosphatase and conductive loss.
B. Osteopetrosis
Osteopetrosis is a rare disorder of dense brittle bone, usually presenting in childhood with marrow failure.
C. Paget disease of bone (correct)
Correct. Skull enlargement, bone pain and high alkaline phosphatase with mixed loss indicate Paget disease.
D. Presbycusis
Presbycusis is a symmetric sensorineural loss of ageing without bone disease.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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